Details

• Brand:

  

• SKU:

  21049-ZL80A

• Positions: Lower, Left, Outer, Front
• Other Names:

  Connector Pipe O-Ring, Gasket, Seal Ring, Engine Coolant Thermostat Housing O-Ring, Thermostat Housing O-Ring, Water Pipe O-Ring, Seal O-Ring

• Description:

  Description:

  Genuine OEM Nissan Engine Coolant Pipe O-Ring Seal — Part # 21049-ZL80A

  Replace your coolant pipe O-ring with the factory-correct seal for Nissan's 3.5L and 4.0L V6 platforms. This genuine OEM O-ring seals coolant pipe and oil cooler connector connections throughout the cooling system — used at multiple locations including the front lower coolant pipe, oil cooler connector, and water pump housing on both the VQ35DE and VQ40DE engine families. A critical single-use seal that spans 30 years and over 1,100 vehicle variants across Nissan's most popular models.

  Part Details:

  • Part Number: 21049-ZL80A
  • Replaces: 21049-31U00
  • Other Names: Seal-O Ring, Engine Coolant Pipe O-Ring, Oil Cooler Connector O-Ring, Water Pump Housing Seal, Thermostat Gasket
  • Condition: New, Genuine OEM Nissan
  • Positions: Left, Outer, Front, Lower
  • Applications: 3.5L VQ35DE and 4.0L VQ40DE engines
  • Sold Individually: 1 O-ring per listing — order quantity needed for your repair

  ⚠️ Single-Use — Cannot Be Reused: This O-ring seal cannot be reused or reinstalled once removed. Always replace with a new seal any time the coolant pipe or oil cooler connector is disconnected. Reusing a compressed O-ring risks an immediate coolant leak after installation.

  Compatible Vehicles (Partial List — 1,100+ variants, 1995–2025):

  • 2002–2024 Nissan Altima (3.5L VQ35DE — L32, L33, L34)
  • 2004–2024 Nissan Armada (5.6L and 3.5L — TA60)
  • 2005–2021 Nissan Frontier (4.0L VQ40DE — D40, D41)
  • 2000–2024 Nissan Maxima (3.5L VQ35DE — A35, A36)
  • 2003–2025 Nissan Murano (3.5L VQ35DE — Z52)
  • 2000–2024 Nissan Pathfinder (3.5L and 4.0L — R51, R52, R53)
  • 2014–2020 Nissan Rogue (2.5L — T32 — confirm application)
  • 2004–2024 Nissan Titan (3.5L and 5.6L — A60, A61)
  • 2012–2021 Nissan NV Full Size Van (F80, WF80)

  Always confirm fitment using your VIN before purchasing.

  Why buy OEM? Aftermarket coolant pipe O-rings are frequently the wrong durometer, wrong diameter, or wrong material compound for coolant and oil compatibility — causing seepage even when brand new. The genuine Nissan O-ring is manufactured to the exact cross-section, inner diameter, and material specification for a reliable, leak-free seal at these critical cooling system connections.

  When you need this part:

  • Water pump or thermostat replacement — always replace this O-ring
  • Oil cooler service or removal — O-ring must be replaced
  • Coolant leak at the front lower pipe, oil cooler connector, or water pump housing
  • Cooling system service requiring pipe disconnection
  • Preventive replacement during major cooling system or engine work

  Pro tip: Buyers often order 2–3 of these at once — at under $8 MSRP it's inexpensive insurance to have spares on hand for the next cooling system service.

  Ships fast from Walser Nissan Wayzata — an authorized Nissan dealership. Message us your VIN and we'll confirm fitment before you buy.

• Condition: New
• Notes: Part cannot be reused/reinstalled.
• Applications: 4.0L. 3.5L.
• Replaces:

  2104931u00

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